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Blood urea nitrogen ( BUN ) is a medical test that measures the amount of urea nitrogen found in blood. Urea is a waste product formed in the liver when protein is metabolized into its component parts (amino acids). This process produces ammonia, which is then converted into the less toxic waste product urea. Blood urea nitrogen or BUN test measures the amount of urea nitrogen in the blood.
Nitrogen is a component of both ammonia and urea. Urea and urea nitrogen are referred to somewhat interchangeably because urea contains nitrogen and because urea/urea nitrogen is the "transport method" used by the body to rid itself of excess nitrogen. Urea is released by the liver into the blood and is carried to the kidneys, where it is filtered out of the blood and released into the urine. Since this is an ongoing process, there is usually a small but stable amount of urea nitrogen in the blood.
Most diseases or conditions that affect the kidneys or liver have the potential to affect the amount of urea present in the blood. If increased amounts of urea are produced by the liver or if the kidneys are not working properly and have difficulty filtering wastes out of the blood, then urea concentrations will rise in the blood. If significant liver damage or disease inhibits the production of urea, then BUN concentrations may fall.
BUN; Urea Nitrogen; Urea; Blood Urea Nitrogen
BUN or Blood Urea Nitrogen test is prescribed to evaluate:
Blood urea nitrogen levels can also help identify damage to body systems and diseases of the digestive, circulatory, and respiratory systems.
BUN or Blood Urea Nitrogen test is part of both the BMP and CMP, groups of tests that are widely used:
Some signs and symptoms of kidney dysfunction include:
BUN or Blood Urea Nitrogen test also may be ordered: