Low-density lipoprotein (LDL cholesterol, LDL-C) is one type of lipoprotein that carries cholesterol in the blood. LDL-C consists mostly of cholesterol and similar substances with a small amount of protein. Most often, this test involves using a formula to calculate the amount of LDL-C in blood based on results of a lipid profile. Occasionally, LDL-C is measured directly.
Artery plaqueMonitoring and maintaining healthy levels of lipids is important for staying healthy. Eating too much of foods that are high in saturated fats and trans unsaturated fats (trans fats) or having an inherited predisposition can result in a high level of cholesterol in the blood. The extra cholesterol may be deposited in plaques on the walls of blood vessels. Plaques can narrow or eventually block the opening of blood vessels, leading to hardening of the arteries (atherosclerosis) and increased risk of numerous health problems, including heart disease and stroke. Photo source: NHLBI
LDL-C is considered to be undesirable and is often called ""bad"" cholesterol because it deposits excess cholesterol in blood vessel walls and contributes to hardening of the arteries and heart disease. This is in contrast to high-density lipoproteins (HDL) that tend to transport cholesterol from the arteries to the liver. HDL is thought to protect against heart disease and so it is often called ""good"" cholesterol.
The LDL-C test can help determine an individual's risk of heart disease and help guide decisions about what treatment may be best if the person is at borderline or high risk. The results are considered along with other known risk factors of heart disease to develop a plan of treatment and follow up. Treatment options may involve lifestyle changes such as diet and exercise or lipid-lowering medications such as statins.
The results of a standard lipid profile, which consists of total cholesterol, HDL-C, and triglycerides, are usually used to calculate the amount of LDL-C in the blood. The results are entered into a formula that calculates the amount of cholesterol present in LDL (see Common Questions #3). In most cases, the formula provides a good estimate of the LDL-C, but it becomes less accurate with increased triglyceride levels when, for example, a person has not fasted before having blood drawn. In this situation, the only way to accurately determine LDL-C is to measure it directly. Direct measurement of LDL-C is less affected by triglycerides and can be used when an individual is not fasting or has significantly elevated triglycerides (above 400 mg/dL).
LDL; LDL-C; Low-Density Lipoprotein Cholesterol
Heart Disesse; Obesity; Hypertension; Diabetes; Stroke; Athrosclerosis
To determine your risk of developing heart disease; to monitor effectiveness of lipid-lowering therapy. Screening: as part of a health exam with a lipid profile; every four to six years in adults with no risk factors for heart disease; youth should be tested at least once between the ages of 9 and 11 and once again between the ages of 17 and 21.
Monitoring: may be done more frequently and at regular intervals when risk factors for heart disease are present, when prior results showed high risk levels, and/or when undergoing treatment for unhealthy lipid levels.
LDL-C levels may be ordered as part a lipid profile when a person has a routine health exam. It is recommended that all adults with no risk factors for heart disease be tested every four to six years.
For people who have one or more major risk factors for heart disease (see below), a fasting lipid profile may be ordered more frequently. It may also be ordered when someone has had a high screening cholesterol result to see if the total cholesterol is high because of too much LDL-C.
Major risk factors for heart disease other than a high LDL-C include:
[Note: High HDL-C (60 mg/dL or above) is considered a ""negative risk factor"" and its presence allows the removal of one risk factor from the total.]
For children and adolescents, routine lipid testing is recommended by the American Academy of Pediatrics once between the ages of 9 and 11 and again between the ages of 17 and 21. Earlier and more frequent screening with a lipid profile is recommended for children and youth who are at increased risk of developing heart disease as adults. Some of the risk factors are similar to those in adults and include a family history of heart disease or health problems such as diabetes, high blood pressure, or being overweight. High-risk children should have their first lipid profile between 2 and 8 years of age. Children younger than 2 years old are too young to be tested.
LDL-C levels may also be ordered at regular intervals to evaluate the success of lipid-lowering lifestyle changes such as diet and exercise or to determine the effectiveness of drug therapy such as statins. Guidelines from the American College of Cardiology and the American Heart Association recommend that adults taking statins have a fasting lipid profile done 4 to 12 weeks after starting therapy and then every 3 to 12 months thereafter to assure that the drug is working.
We at iHealthMantra enable patients to book their diagnostics tests from best Diagnostics Labs in India such as Thyrocare, Dr Lal Pathlabs, Metropolis, Suburban Diagnostics, Medall Clumax and many others top quality diagnostic labs. Diagnostics tests booked through us are at low price and patients can avail free home sample collection.
We also provide preventive health checkups, Regular Health check-up, Health checkup packages, Thyroid Profile, PET Scan, MRI Scan, CT Scan, Full body check up, Vitamin D Profile, Lipid Profile, Renal Function Tests and other blood tests. Provided below is a brief description of few of our partner labs.
Thyrocare, with its tag line of Think Thyroid, Think Thyrocare, is India's first fully automated diagnostic laboratory with a focus on providing quality at affordable costs to retail customers, laboratories and hospitals in India and other countries. Thyrocare has strong focus on technology, brand and systems that enables Thyrocare laboratories to give their clients the best of science and technology at an affordable cost. Thyrocare laboratories have NABL and CAP accreditations. Thyrocare supports home sample collection to provide convenience to customers.Thyrocare is a PAN India chain with services across all the major Indian cities such New Delhi, Mumbai, Pune, Bangalore, Chennai, Hyderabad and Kolkata.
Key tests and health profiles supported by Thyrocare are: T3, T4, TSH also called Thyroid Profile, TSH also called Thyroid Stimulating Hormone, Thyrocare Aarogyam Packages such as Mini Aarogyam, Aarogyam A, Aarogyam B, Aarogyam C, Vitamin Profiles such as Vitamin D Profile and Vitamin D3 test.
Metropolis is India?s one of the biggest and multinational chain of pathology labs and diagnostics centre known for excellent customer satisfaction and preventive healthcare. Metropolis has following accreditations, CAP, NABL and RNTCP. Metropolis Healthcare has been honoured for its best practices and its commitment to excellence in customer satisfaction and innovation. The journey of Metropolis started in 1981, when its Founder and Chairman, Dr. Sushil Shah had a vision to introduce specialized testing facilities to the Indian population. Processing over 30 million tests a year, catering to over 20,000 Laboratories, Hospitals, Nursing Homes and 2,00,000 consultants; and with 34 years of experience in delivering accurate reports, Metropolis has earned the reputation of being India's multinational chain of laboratories with a strong presence in Sri Lanka, UAE, South Africa, Kenya, Mauritius & Ghana. Metropolis supports home sample collection to provide convenience to customers. Metropolis is a PAN India chain with services across all the major Indian cities such New Delhi, Mumbai, Pune, Bangalore, Chennai and Hyderabad.
Common Tests supported by Metropolis are Lipid Profile, Thyroid Profile, Vitamin D Profile, Renal function test, Blood Tests, Vitamin D3, TSH, T3, T4, Diabetes Test, ECG test, thalassemia test, preventive health checkups, Regular Health check-up, Health checkup packages and Full body check up.
About Dr Lal Pathlabs
Dr Lal PathLabs is a leading Diagnostic Centre and Pathology Lab for Blood Test in India. Dr Lal PathLabs has a strong focus on quality with NABL accreditation. Dr Lal PathLabs has a qualified team of Pathologists, Radiologists, Microbiologists, Biochemists and specialists. Dr Lal PathLabs supports home sample collection to provide convenience to customers. Dr Lal PathLabs is a PAN India chain with services across all the major Indian cities such New Delhi, Mumbai, Pune, Bangalore, Chennai, Hyderabad and Kolkata.
Common Tests supported by Dr Lal PathLabs are Lipid Profile, Thyroid Profile, Vitamin D Profile, Renal function test, Blood Tests, Vitamin D3, TSH, T3, T4, Diabetes Test, ECG test, thalassemia test, preventive health checkups, Regular Health check-up, Health checkup packages and Full body check up. Few unique health packages supported by Dr Lal PathLabs are Swasth Plus Basic Health Checkup, Swasth Plus Advanced Health Checkup and Swasth Plus Vitamins Package.
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