"Alkaline phosphatase (ALP) is an enzyme found in several tissues throughout the body. The highest concentrations of ALP are present in the cells that comprise bone and the liver. Elevated levels of ALP in the blood are most commonly caused by liver disease or bone disorders. This test measures the level of ALP in the blood. In the liver, ALP is found on the edges of cells that join to form bile ducts, tiny tubes that drain bile from the liver to the bowels, where it is needed to help digest fat in the diet. ALP in bone is produced by special cells called osteoblasts that are involved in the formation of bone. Each of the various tissue types produces distinct forms of ALP called isoenzymes.
You may have to fast for 10-12 hours without any intake of food and drinks before the test.If you are on any medications, have any allergies or underlying medical conditions before your Alkaline Phosphatase. Your doctor will give specific instructions depending on your condition on how to prepare for Alkaline Phosphatase.
The normal test results may vary depending on the gender, age, health history, your condition, etc. Teenagers have high levels of alkaline phosphatase test results due to the rapid development of their bones. Pregnancy also causes higher levels of alkaline phosphatase.
If your test results are higher than the normal range it may indicate conditions like osteoblastic bone tumors, liver disease like hepatitis, blood cancer (leukemia), Paget disease (type of bone condition), rickets (weak or soft bones in children), sarcoidosis (collection of inflammatory cells in different parts of the body), lymphoma (cancer of lymph glands), hyperparathyroidism, etc
If your test results are lower than the normal range it may indicate conditions like alcoholic liver disease, gallstones, blockage of biliary ducts, renal cell carcinoma, giant cell arteritis, pancreatitis, multiple endocrine neoplasias II, etc.
Abnormal test results may rarely indicate conditions like malnutrition, anemia, Wilson's disease, celiac disease, prostate cancer, breast cancer, ulcerative colitis, etc.
If you get abnormal test results, consult your doctor immediately. Your doctor may recommend other tests depending on your results.
Gender Age groups Value
OTHER All age groups 44 - 147 IU/L