Luteinising Hormone:Luteinising Hormone (LH)
"Luteinizing hormone (LH) is a hormone associated with reproduction and the stimulation of the release of an egg from the ovary (ovulation) in women and testosterone production in men. This test measures the amount of luteinizing hormone in the blood or urine. LH is produced by the pituitary gland, a grape-sized organ found at the base of the brain. Control of LH production is a complex system involving the hypothalamus in the brain, the pituitary gland, and the hormones produced by the ovaries and testicles.
Inform your doctor if you are on any medications, have any allergies or underlying medical conditions before your LH. Your doctor will give specific instructions depending on your condition on how to prepare for LH.
No specific preparation is required for this test. Your doctor may ask you to stop taking certain medications such as birth control pills or other hormone pills for up to four weeks before the test. You are also advised to inform the doctor if you have had any test with a radioactive substance in the past 7 days. If this test is being performed with any other tests, you may need to fast (not eat or drink) for up to eight hours leading up to the test; your doctor will provide specific instructions in this case.
If the test result falls within the normal reference range, you have an adequate level of LH and no medical intervention is necessary.
In women, increased levels of LH may indicate a condition called primary ovarian failure, where the ovaries fail to work properly. Many conditions such as autoimmune disorders, ovarian tumors, Turner syndrome (a genetic abnormality), polycystic ovary syndrome, adrenal diseases, thyroid diseases, etc. may lead to primary ovarian failure. Women with underdeveloped ovaries and women undergoing chemotherapy or radiation therapy may also exhibit increased LH levels. Decreased levels of LH may indicate secondary ovarian failure. This condition may be caused by disorders of the pituitary gland or hypothalamus.
In men, the increased levels of LH indicate primary testicular failure, a condition where the testes are unable to work properly. Many conditions such as autoimmune disorders, germ cell tumors (a type of cancer), Klinefelter syndrome (a genetic abnormality), some viral infections such as mumps, etc. may lead to primary testicular failure. Men with underdeveloped testes and men undergoing chemotherapy or radiation therapy may also exhibit increased levels of LH. Decreased levels of LH may indicate secondary testicular failure. This condition may be caused by disorders of the pituitary gland or hypothalamus. Testicular failure may lead to symptoms such as a decreased sexual drive, tiredness, sexual dysfunction, low muscle mass, etc.
This test is useful to understand if the symptoms have been caused by a disorder of the pituitary gland or the hypothalamus. After measuring the baseline LH levels, a dose of gonadotropin is injected into the individuals. An increase in LH levels indicates a hypothalamus disorder while a decrease in LH levels indicates a pituitary disorder.
In children, increased levels of LH may indicate early onset of puberty. In delayed puberty, the LH levels may be normal or lower than normal. Many genetic conditions, some type of cancers, chronic infections, some types of traumas, etc. may result in abnormal LH levels.
If you have higher or lower than normal levels of the LH hormone, consult your doctor for further instructions. Based on the test results, your doctor may advise appropriate medical treatments, lifestyle modifications, or further diagnostic tests.
Gender Age groups Value
FEMALE All age groups 2 - 18 mIU/ml
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