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Hepatitis B Virus (HBV) HBV-DNA detection by PCR (CSF)

Hepatitis B Virus (HBV) HBV-DNA detection by PCR (CSF)

Overview

Preparation(Before)

A Hepatitis B (HBV) Blood Test Panel includes a Hepatitis B Core Antibody Total (Test #006718), Hepatitis B Surface Antigen (Test #006510), Hepatitis B Surface Antibody (Test #006395). Preparation: No fasting required.

Benefits

Used to detect previous exposure to HBV; it can also develop from successful vaccination so it is used to determine the need for vaccination (if anti-HBs is absent) or to determine if a person has recovered from an infection and is immune (cannot get the infection again)

Common uses

A hepatitis B surface antibody test is used to check for immunity to HBV. A positive test means you are immune to hepatitis B. There are two possible reasons for a positive test. You may have been vaccinated, or you may have recovered from an acute HBV infection and are no longer contagious.

Global facts

Hepatitis B is a viral infection that attacks the liver and can cause both acute and chronic disease.

  • The virus is most commonly transmitted from mother to child during birth and delivery, as well as through contact with blood or other body fluids, including sex with an infected partner, injection-drug use that involves sharing needles, syringes, or drug-preparation equipment and needle sticks or exposures to sharp instruments.
  • WHO estimates that in 2015, 257 million people were living with chronic hepatitis B infection (defined as hepatitis B surface antigen positive).
  • In 2015, hepatitis B resulted in an estimated 887 000 deaths, mostly from cirrhosis and hepatocellular carcinoma (i.e. primary liver cancer).
  • As of 2016, 27 million people (10.5% of all people estimated to be living with hepatitis B) were aware of their infection, while 4.5 million (16.7%) of the people diagnosed were on treatment. According to latest WHO estimates, the proportion of children under five years of age chronically infected with HBV dropped to just under 1% in 2019 down from around 5% in the pre-vaccine era ranging from the 1980s to the early 2000s.
  • Hepatitis B can be prevented by vaccines that are safe, available and effective.

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