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Thyroid Function Panel

Thyroid Function Panel

Overview

Thyroid function tests are used to check whether your thyroid is working normally.

The most common thyroid function tests are:

Free T4 (the main thyroid hormone in your blood ? a precursor for T3) TSH (the hormone from the pituitary gland that stimulates the thyroid to produce T4) Total T3 (the active form of the hormone ? T4 is converted to T3) If you are being screened for thyroid disease, often only the thyroid stimulating hormone (TSH) test may be needed.

Other thyroid tests include:

Total T4 (the free hormone and the hormone bound to carrier proteins) Free T3 (the free active hormone) T3 resin uptake (an older test that is rarely used now) Thyroid uptake and scan Thyroid binding globulin Thyroglobulin The vitamin biotin (B7) can affect the results of many thyroid hormone tests. If you take biotin, talk to your provider before you have any thyroid function tests.

Preparation(Before)

No test preparation is needed. However, certain medications, multivitamins and supplements can interfere with thyroid testing, so tell your healthcare practitioner about any prescribed or over-the-counter drugs and/or supplements that you are taking. If you take thyroid hormone as treatment for thyroid disease, it is recommended that your blood sample be drawn before you take your dose for that day. Acute illness may affect thyroid hormone test results. It is generally recommended that thyroid testing be avoided in hospitalized patients or postponed until after you have recovered from the illness

Result explanation

The T4 test and the TSH test are the two most common thyroid function tests. They?re usually ordered together.

The T4 test is known as the thyroxine test. A high level of T4 indicates an overactive thyroid (hyperthyroidism). Symptoms include anxiety, unplanned weight loss, tremors, and diarrhea. Most of the T4 in your body is bound to protein. A small portion of T4 is not and this is called free T4. Free T4 is the form that is readily available for your body to use. Sometimes a free T4 level is also checked along with the T4 test.

The TSH test measures the level of thyroid-stimulating hormone in your blood. The TSH has a normal test range between 0.4 and 4.0 milli-international units of hormone per liter of blood (mIU/L).

If you show signs of hypothyroidism and have a TSH reading above 2.0 mIU/L, you?re at risk for progressing to hypothyroidism. Symptoms include weight gain, fatigue, depression, and brittle hair and fingernails. Your doctor will likely want to perform thyroid function tests at least every other year going forward. Your doctor may also decide to begin treating you with medications, such as levothyroxine, to ease your symptoms.

Both the T4 and TSH tests are routinely performed on newborn babies to identify a low-functioning thyroid gland. If left untreated, this condition, called congenital hypothyroidism, can lead to developmental disabilities.

T3 results The T3 test checks for levels of the hormone triiodothyronine. It?s usually ordered if T4 tests and TSH tests suggest hyperthyroidism. The T3 test may also be ordered if you?re showing signs of an overactive thyroid gland and your T4 and TSH aren?t elevatedTrusted Source.

The normal range for the T3 is 100?200 nanograms of hormone per deciliter of blood (ng/dL). Abnormally high levels most commonly indicate a condition called Grave?s disease. This is an autoimmune disorder associated with hyperthyroidism.

T3 resin uptake results A T3 resin uptake, also known as a T3RU, is a blood test that measures the binding capacity of a hormone called thyroxin-binding globulin (TBG). If your T3 level is elevated, your TBG binding capacity should be low.

Abnormally low levels of TBG often indicate a problem with the kidneys or with the body not getting enough protein. Abnormally high levels of TBG suggest high levels of estrogen in the body. High estrogen levels may be caused by pregnancy, eating estrogen-rich foods, obesity, or hormone replacement therapy.nction tests.

StackEdit Viewer Synchronize Open, save, collaborate in the Cloud Publish Export to the web Sharing Share document links Import from disk Export to disk Import from URL Convert HTML to Markdown Settings About New document Delete document Manage documents Find document Hello! The T4 test and the TSH test are the two most common thyroid function tests. They?re usually ordered together.

The T4 test is known as the thyroxine test. A high level of T4 indicates an overactive thyroid (hyperthyroidism). Symptoms include anxiety, unplanned weight loss, tremors, and diarrhea. Most of the T4 in your body is bound to protein. A small portion of T4 is not and this is called free T4. Free T4 is the form that is readily available for your body to use. Sometimes a free T4 level is also checked along with the T4 test.

The TSH test measures the level of thyroid-stimulating hormone in your blood. The TSH has a normal test range between 0.4 and 4.0 milli-international units of hormone per liter of blood (mIU/L).

If you show signs of hypothyroidism and have a TSH reading above 2.0 mIU/L, you?re at risk for progressing to hypothyroidism. Symptoms include weight gain, fatigue, depression, and brittle hair and fingernails. Your doctor will likely want to perform thyroid function tests at least every other year going forward. Your doctor may also decide to begin treating you with medications, such as levothyroxine, to ease your symptoms.

Both the T4 and TSH tests are routinely performed on newborn babies to identify a low-functioning thyroid gland. If left untreated, this condition, called congenital hypothyroidism, can lead to developmental disabilities.

T3 results The T3 test checks for levels of the hormone triiodothyronine. It?s usually ordered if T4 tests and TSH tests suggest hyperthyroidism. The T3 test may also be ordered if you?re showing signs of an overactive thyroid gland and your T4 and TSH aren?t elevatedTrusted Source.

The normal range for the T3 is 100?200 nanograms of hormone per deciliter of blood (ng/dL). Abnormally high levels most commonly indicate a condition called Grave?s disease. This is an autoimmune disorder associated with hyperthyroidism.

T3 resin uptake results A T3 resin uptake, also known as a T3RU, is a blood test that measures the binding capacity of a hormone called thyroxin-binding globulin (TBG). If your T3 level is elevated, your TBG binding capacity should be low.

Abnormally low levels of TBG often indicate a problem with the kidneys or with the body not getting enough protein. Abnormally high levels of TBG suggest high levels of estrogen in the body. High estrogen levels may be caused by pregnancy, eating estrogen-rich foods, obesity, or hormone replacement therapy.nction tests.

StackEdit Viewer Synchronize Open, save, collaborate in the Cloud Publish Export to the web Sharing Share document links Import from disk Export to disk Import from URL Convert HTML to Markdown Settings About New document Delete document Manage documents Find document Hello!

Common uses

A thyroid panel may be used to evaluate thyroid function and/or help diagnose thyroid disorders.

Typically, the preferred initial test for thyroid disorders is a TSH test. If the TSH level is abnormal, it will usually be followed up with a test for free T4. Sometimes a total T3 or free T3 will also be performed. Often, the laboratory will do this follow-up testing automatically. This is known as reflex testing and it saves the healthcare practitioner time from having to wait for the results of the initial test and then requesting additional testing to confirm or clarify a diagnosis. Reflex tests are typically performed on the original sample that was submitted when the initial test was requested.

As an alternative, a thyroid panel may be requested by your healthcare practitioner. This means that all three tests will be performed at the same time to get a more complete initial picture of thyroid function

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