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Acid-fast bacillus (AFB) is a type of bacteria that causes tuberculosis and certain other infections. Tuberculosis, commonly known as TB, is a serious bacterial infection that mainly affects the lungs. It can also affect other parts of the body, including the brain, spine, and kidneys. TB is spread from person to person through coughing or sneezing.

TB can be latent or active. If you have latent TB, you?ll have TB bacteria in your body but won?t feel sick and can?t spread the disease to others. If you have active TB, you?ll have symptoms of the disease and could spread the infection to others.

AFB tests are usually ordered for people with symptoms of active TB. The tests look for the presence of AFB bacteria in your sputum. Sputum is a thick mucus that is coughed up from the lungs. It is different from spit or saliva.

There are two main types of AFB tests:

AFB smear. In this test, your sample is ?smeared? on a glass slide and looked at under a microscope. It can provide results in 1?2 days. These results can show a possible or likely infection, but can?t provide a definite diagnosis. AFB culture. In this test, your sample is taken to a lab and put in a special environment to encourage the growth of bacteria. An AFB culture can positively confirm a diagnosis of TB or other infection. But it takes 6?8 weeks to grow enough bacteria to detect an infection. Other names: AFB smear and culture, TB culture and sensitivity, mycobacteria smear and culture

What are they used for? AFB tests are most often used to diagnose an active tuberculosis (TB) infection. They may also be used to help diagnose other types of AFB infections. These include:

Leprosy, a once feared, but rare and easily treatable disease that affects the nerves, eyes, and skin. Skin often becomes red and flaky, with loss of feeling. An infection similar to TB that mostly affects people with HIV/AIDS and others with weakened immune systems. AFB tests may also be used for people who have already been diagnosed with TB. The tests can show if the treatment is working, and whether the infection can still be spread to others.

Why do I need an AFB test? You may need an AFB test if you have symptoms of active TB. These include:

Cough that lasts for three weeks or more Coughing up blood and/or sputum Chest pain Fever Fatigue Night sweats Unexplained weight loss Active TB can cause symptoms in other parts of the body besides the lungs. Symptoms vary depending on which part of the body is affected. So you may need testing if you have:

Back pain Blood in your urine Headache Joint pain Weakness You may also need testing if you have certain risk factors. You may be at higher risk of getting TB if you:

Have been in close contact with someone who has been diagnosed with TB Have HIV or another disease that weakens your immune system Live or work in a place with a high rate of TB infection. These include homeless shelters, nursing homes, and prisons.



Result explanation

If your results on an AFB smear or culture were negative, you probably don?t have active TB. But it could also mean there weren?t enough bacteria in the sample for your health care provider to make a diagnosis.

If your AFB smear was positive, it means you probably have TB or other infection, but an AFB culture is needed confirm the diagnosis. Culture results can take several weeks, so your provider may decide to treat your infection in the meantime.

If your AFB culture was positive, it means you have active TB or another type of AFB infection. The culture can identify which type of infection you have. Once you have been diagnosed, your provider may order a ?susceptibility test? on your sample. A susceptibility test is used to help determine which antibiotic will provide the most effective treatment.

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