"Vitamin B12 and folate are two vitamins that are part of the B complex of vitamins. They are necessary for normal red blood cell (RBC) formation, repair of tissues and cells, and synthesis of DNA, the genetic material in cells. Both are nutrients that cannot be produced in the body and must be supplied by the diet.
Vitamin B12 and folate tests measure vitamin levels in the liquid portion of the blood (serum or plasma) to detect deficiencies. Sometimes the amount of folate inside red blood cells may also be measured.
Inform your doctor if you are on any medications, have any allergies or underlying medical conditions before your Serum B12. Your doctor will give specific instructions depending on your condition on how to prepare for Serum B12.
This test is done after you fast (without eating anything) for a whole night or for 8 to 12 hours. Usually, the blood is drawn in the morning after an overnight fasting.
There is no need for medical interventions if test results are in normal range. If the test results are more than the normal range then there may be a chance for Diabetes mellitus, heart failure, AIDS, severe liver disease, obesity etc.
If test results are less than the normal range, then it indicates that there may be a chance for pernicious anemia (decrease in red blood cells as the body cannot absorb enough vitamin-B12), Crohn's disease (redness and swelling in the lining of the digestive tract), inflammatory bowel disease, chronic alcoholism (heavy drinking of alcohol), low consumption of the diet containing vitamin-B12, malabsorption etc.
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